Obesity arises from an imbalance between adipogenesis and adipocyte thermogenesis. IL-27 suppresses adipogenesis, prevents weight gain, and improves glucose and lipid metabolic homeostasis in high ...

Despite the high prevalence and morbidity of osteoarthritis (OA), an effective treatment for this disease is currently lacking. Restoration of the diseased articular cartilage in patients with OA ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

These cells are often found in heterogeneous tumors and include cancer stem-like cells (CSCs), cells undergoing epithelial-to ...