Ulcerative colitis may lead to toxic megacolon when inflammation in the colon’s inner lining reaches the inner areas of the large intestine. This causes your large intestine to stop working and ...

As its name suggests, toxic megacolon is a serious complication that can occur in people who have inflammatory bowel disease (IBD). The condition is more common in people with ulcerative colitis ...

Considered the most serious complication of ulcerative colitis, toxic megacolon is the most extreme (and potentially life-threatening) form of fulminant colitis. It’s rare, ...

Almost half of all toxic megacolon cases are triggered by inflammatory bowel diseases (IBDs), like ulcerative colitis. Prompt medical treatment is vital to minimize the risk of complications.

Considered the most serious complication of ulcerative colitis, toxic megacolon is the most extreme (and potentially life-threatening) form of fulminant colitis. It’s rare, ...

It also can cause toxic megacolon, which damages the deeper layers of the colon. People with uncontrolled ulcerative colitis are also at increased risk for toxic megacolon.

A person may develop toxic megacolon if their colon has inflammation due to conditions such as Crohn’s disease or ulcerative colitis, or infections such as Clostridioides difficile (C. difficile).

Severe relapse of ulcerative colitis and toxic megacolon has been documented in the presence of coexisting infections such as C. difficile or CMV; therefore, these infections have to be excluded.

Fulminant colitis progresses rapidly, causing severe inflammation, systemic toxicity, and complications like toxic megacolon, bowel perforation, and sepsis. Prompt treatment can reduce these risks ...

Another life threatening complication is toxic megacolon where the gases become trapped inside the colon, causing it to swell. Those with ulcerative colitis are also at a raised risk for ...

Ulcerative Colitis: When Surgery Must Be Considered ... The most obvious candidates are those in whom colonic perforation has occurred or is believed to be imminent (as in toxic megacolon, ...

In general, ulcerative colitis has an incidence of 9–20 cases per 100,000 persons per year, according to StatPearls Publishing. The research further notes that its prevalence is 156-291 cases ...