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Using proteases to screen and validate ADC linker
ACROBiosystems has developed a series of specialized proteases for the screening and validation of ADC linkers, focusing on ...
Bacteria hijack tick cell defenses to spread disease, study shows
Washington State University researchers have discovered how the bacteria that cause anaplasmosis and Lyme disease hijack ...
C&EN4d
Machine Learning Reveals the Critical Interactions for SARS-CoV-2 Spike Protein Binding to ACE2 | The Journal of Physical Chemistry Letters - ACS Publications
SARS-CoV and SARS-CoV-2 bind to the human ACE2 receptor in practically identical conformations, although several residues of the receptor-binding domain (RBD) differ between them. Herein, we have used ...
C&EN4d
Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19
In the search for inhibitors of COVID-19, we have targeted the interaction between the human angiotensin-converting enzyme 2 (ACE2) receptor and the spike receptor binding domain (S1-RBD) of ...