Washington State University researchers have discovered how the bacteria that cause anaplasmosis and Lyme disease hijack ...

Researchers have produced multimeric, ultra-sensitive aptamers that have potential in both diagnostic and therapeutic ...

Among the defining achievements of SG60 is Singapore’s transformation into a global health innovator. The latest chapter ...

Scientists have unearthed a rare class of ultra-potent antibodies derived from llamas that can neutralize a vast array of coronaviruses—including SARS-CoV-1 and multiple forms of SARS-CoV-2, both old ...

The team used a similar approach to model the dynamic transformations that the SARS-CoV-2 Spike protein undergoes after binding its receptor and while literally moving towards fusion. To accomplish ...

Multidisciplinary AI- and physics-driven modeling of the viral fusion process has enabled the discovery of an orally available drug inhibiting infection with multiple coronaviruses.

Though it is near the receptor-binding domain and is known to be targeted by some antibodies, function of the N-terminal domain in SARS-CoV-1 and -2 spike proteins is not completely understood.

Dec. 8, 2020 — The binding of a SARS-CoV-2 virus surface protein spike -- a projection from the spherical virus particle -- to the human cell surface protein ACE2 is the first step to infection ...

Each monomer of the spike protein shows the receptor binding domain (RBD) in green, orange and magenta, which contains a receptor binding motif in cyan on the top. Mutations emerged in the SARS ...

Mutations in SARS-CoV-2 spike protein receptor-binding domains may result in escape variants resistant to therapeutics and vaccines. ScienceDaily . Retrieved May 3, 2025 from www.sciencedaily.com ...

It could make the virus’s spike protein unstable so that it can’t latch quickly onto a cell, for example. But inside someone with a weak immune system, viruses may be able to gain a new ...