Researchers from Lawrence Livermore National Laboratory (LLNL), in collaboration with other leading institutions, have ...

Researchers develop quinoline-based drug with inhibitory activity against the SARS-CoV-2 papain-like protease (PLpro).

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines helped control the spread of the virus, the emergence of new variants ...

A recent finding in Nature showed that the spike protein of SARS-CoV-2 binds with fibrinogen, leading to thrombo-inflammation. This raises a fundamental question: Why does the virus need to bind with ...

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about its future evolution remain. New variants of the virus will likely emerge, ...

COVID-19 has continued to alarm public health, and although several therapeutics and vaccines have been developed, the development of effective vaccines or antibodies is challenging due to mutations ...

These compounds can be categorized by the type of reactive group, or “warhead”, they contain (Figure 2). Michael acceptors form a thioether ... numerous novel hits active in biochemical and live virus ...

The organelles were labeled with antibodies against marker proteins of ... followed by nasal inoculation with 50µl SARS-CoV-2 virus at a dosage of 10 5.5 TCID50/mL (created using BioRender.com). IB ...

Hypochlorous acid is safe enough to spray in your eyes yet more effective than bleach. Why isn’t it everywhere?

Treatments for COPD, psoriasis, and neuroendocrine tumors, as well as a next-generation COVID-19 vaccine are under review.