As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every ...

The spike protein of the coronavirus, or SARS-CoV-2, binds to ACE2, a receptor on the host cells ... “We simulated the electronic structure of the two interacting molecules and assessed how amino ...

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

The model can predict which mutations are likely to occur by looking for mutations that cause only small changes in the protein's structure and function. This is important because, in most cases, ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

Viruses like SARS-CoV-2 use sugar molecules to hide from the immune system, but scientists at Scripps Research have designed ...

CoV-2, a new merbecovirus found in bats across China, that utilises the ACE2 receptor for cellular entry—raising concerns ...

SARS-CoV-2, the virus responsible for COVID-19 ... However, mutations in the spike protein can alter its structure, reducing the effectiveness of these inhibitors. In a significant breakthrough, a ...