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Multidisciplinary AI- and physics-driven modeling of the viral fusion process has enabled the discovery of an orally available drug inhibiting infection with multiple coronaviruses.
WYS-633 also prevented SARS-CoV-1, MERS, and multiple SARS-CoV-2 variants from infecting cells ... discovery of drugs against a number of other virus families utilizing membrane fusion proteins, ...
2d
News-Medical.Net on MSNMacrophage-derived lipocalin 2 drives severe pneumonia in SARS-CoV-2 infectionSince the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying ...
5d
News-Medical.Net on MSNWHO Scientific Advisory Group for the Origins of Novel Pathogens reports on SARS-CoV-2 originsThe WHO Scientific Advisory Group for the Origins of Novel Pathogens (SAGO), a panel of 27 independent, international, ...
The human body is naturally equipped with defenses to fight off viral infections. For a virus to successfully infect it, it must first overcome these defenses. To do so, viruses have evolved ...
The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections. To aid ...
The COVID-19 pandemic caused by SARS-CoV-2 presents a global health emergency. Therapeutic options against SARS-CoV-2 are still very limited but urgently required. Molecular tweezers are ...
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