In the shadows of Python Cave, Uganda, a leopard leaps from a guano mound—formed by bat excrement—and sinks its teeth into a ...

The activation of JNK1 occurs during the late stage of the SARS-CoV-2 life cycle, which in turn activates the E3 ligase activity of ITCH (pink arrows). ITCH promotes ubiquitination of the E and M ...

The authors investigated the role of an E3 ubiquitin ligase ITCH in regulating the viral life cycle of SARS-CoV-2. The authors showed that ITCH mediates ubiquitination of the membrane (M) and envelope ...

Virus tropism is governed by multiple factors at the host-virus interface, determining infection outcomes in individual ... and convergent selection of viral mutations. These data expand our ...

Virus tropism is governed by multiple factors at the host-virus interface, determining infection outcomes in individual cells, tissues, ... These data expand our understanding of TMPRSS2’s role in the ...

3 RNF5 in virus life cycle. The role for RNF5 in virus life cycle is gradually unfolding. Recent findings have revealed that RNF5 plays a role in limiting the replication and virulence of SARS-CoV-2 ...

AFM enhances virus research by allowing high-resolution imaging and nanomechanical analysis of viral structures and interactions under physiological conditions. ... HIV, SARS-CoV, MERS, Ebola, and the ...

SARS-CoV-2, the virus that causes COVID-19, has been studied in depth, and now, researchers have put all that knowledge into an incredibly detailed animation that reveals the life cycle of the virus ...

Researchers at the University of Maastricht have produced a unique animated video that visualizes the life cycle of the virus for a ... who earned his Ph.D. with research into the SARS virus, ...

None of them represented the life cycle of the virus itself or incorporated real-life microscopic images as we have done now.’ The animation was produced with Houdini, an animation software package ...

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication.