An easy method for efficiently identifying proteins that interact with bioactive molecules has been developed by chemical biologists at RIKEN. This innovation, published in ChemBioChem, could help to ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in ...

A comprehensive review of the discovery and molecular dissection of the eukaryotic ribosome-associated quality-control pathway for degradation of nascent proteins arising from interrupted translation.

With a new mapping tool, Princeton engineers have revealed how a factory inside cells builds ribosomes, the machinery ...

When ribosomes go rogue Unusual variations in the cellular protein factory can skew development, help cancer spread, and more. But ribosome variety may also play biological roles, scientists say.

A ribosome is composed of two subunits: large and small. During translation, ribosomal subunits assemble together like a sandwich on the strand of mRNA, where they proceed to attract tRNA ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

Racing for the Ribosome Nobel laureate Venki Ramakrishnan’s new book recounts the tale of researchers striving to understand an ancient molecular machine that is essential for all life.

Cell biologists have discovered that a protein, during its synthesis, may destabilize the structure of the ribosome and end its own synthesis prematurely, and found that this phenomenon is used ...

A ribosome is an intercellular structure made of both RNA and protein, and it is the site of protein synthesis in the cell. The ribosome reads the messenger RNA (mRNA) sequence and translates that ...

(Phys.org) —A groundbreaking study of the human ribosome is revealing that the tiny molecular machine is more versatile than previously understood. Minor changes in its sequencing can change its ...

A ribosome itself is a "huge complex of messenger RNA and 50 proteins. Most things in cells are complexes of RNA and proteins." Such simulations are increasing dramatically in sophistication.