While several scientific reports have revealed the distinct regulatory mechanisms of osteoclast and osteoblast differentiation, little is known about the common factors that influence the ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

While several scientific reports have revealed the distinct regulatory mechanisms of osteoclast and osteoblast differentiation, little is known about the common factors that influence the ...

In just 3 years, striking new advances have been made in understanding the molecular mechanisms that govern the crosstalk between osteoblasts ... that results in differentiation and maturation ...

Prostaglandin E2, a class of unsaturated fatty acids with a wide range of physiological activities, is a potent osteoanabolic agent that promotes bone synthesis and increases bone mass by stimulating ...

These deformations produce a variety of stimuli in the cellular microenvironment that can influence the differentiation of marrow stromal cells (MSCs) and the activity of cells of the MSC lineage, ...

Objectives Interleukin (IL)-17 signalling has been shown to be a key regulator of disease in ankylosing spondylitis (AS) with several IL-17 blockers currently clinically approved. Despite this, the ...