Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.
CATUMAXOMAB BECOMES THE ONLY APPROVED DRUG THERAPY FOR MALIGNANT ASCITES, A RARE AND DEBILITATING COMPLICATION OF ADVANCED-STAGE CANCER UNDER A LICENSING AGREEM ...
Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...
Inhibiting GLS1 reduced high blood pressure in the right side of the heart of PAH rats and improved various measures of heart ...
Monocyte-like macrophage (MLM) accumulation precedes colitis-associated ... Besides the temporal changes, we investigated the differences in proinflammatory markers, myeloid cell subsets and ...
We evaluated adenosine deaminase 2 (ADA2), a protein of unknown function released principally by monocytes and macrophages, as a novel biomarker ... minimal association with the inflammatory markers C ...
Modest increases in concentration of C-reactive protein, a circulating marker of inflammation ... Interleukin-8 (or CXCL8) is a chemokine secreted by monocyte/macrophages whose key role in the ...
Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...
Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...
This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...
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