Pulmonary arterial hypertension is caused by narrowing of the blood vessels in the lungs. Learn how it happens, including ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. GA, UNITED STA ...

Q4 2024 Earnings Call Transcript March 20, 2025 Monte Rosa Therapeutics, Inc. beats earnings expectations. Reported EPS is $0 ...

Pint Pharma Announces ANVISA’s Approval of BESREMi® (ropeginterferon alfa-2b) for the Treatment of Polycythemia Vera Pint ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

Hepatitis B virus infection remains one of the leading causes of liver ... Current therapies, such as nucleos(t)ide analogues and interferons, fail to eliminate cccDNA, allowing the virus to rebound ...

Hepatitis B virus (HBV) infection remains an urgent global health concern, affecting hundreds of millions of people and significantly heightening the risk ...

Mohammed K. Sharief, Guy's, King's and St Thomas' School of Medicine, Department of Clinical Neurosciences, Guy's Hospital, London, UK ...

The delta sigH vaccine resulted in a much higher recruitment of critical B and T immune cells to the ... significant difference between the type of interferon triggered. Interferons are proteins ...