CD163 might not be the most exciting name in the world, but behind it lies one of the body's most important defense receptors ...

We thank R. Rajagopal (New York University, New York) for the phospho-TrkB antibody. This work was supported by the National Institutes of Health Grants NS21072 and HD23315 (to M.V.C.) and a European ...

Lab-grown human keratinocytes were fed the quintessential 'bitter pill,' phenylthiocarbamide (PTC), which has been used in all sorts of studies around the genetics of bitter taste. On detecting and ...

No participants from the analytic sample were exposed to synthetic glucocorticoids (e.g., prednisone, betamethasone, dexamethasone) during the prenatal period. Placenta Sample Collection, DNA ...

In this review, we summarize the function of certain anti-diabetic medications with known thermogenic mechanisms and focus on various receptor signaling pathways, such as previously well-known and ...

The T cell receptor (TCR) repertoire encodes immune exposure history ... We explore associations between MHC alleles, immune exposures, and shared TCRs in a large human cohort. Using a previously ...

A comprehensive assessment of the potential for immunogenicity of synthetic receptors requires analysis of all foreign peptide sequences that are present, including fusion sites between human ...

Glucocorticoids (GCs) display both protective and destructive ... Here we report that GCs can selectively activate Trk receptor tyrosine kinases after in vivo administration in the brain and in ...