Total DNA is prepared by proteinase K digestion, phenol-chloroform extraction and precipitation with ethanol, while total RNA is extracted using Trizol ® LS reagent (Invitrogen Life Technologies).

Detection of HCV & Hepadnaviral Genomes in Hepatic Tissue The approach used to identify HCV or hepadnaviral genome sequences in the liver is the same as that in lymphoid cells, except that there ...

A large-scale study tracing human disease history back 37,000 years has identified harmful bacteria, viruses and parasites ...

Indeed, retrospective testing for hepatitis B virus (HBV) markers showed that only 20% of the hepatitis found before antigen screening was related to HBV. The recognition of transfusion-associated ...

Objective The involvement of HBV DNA integration in promoting hepatocarcinogenesis and the extent to which the intrahepatic HBV reservoir modulates liver disease progression remains poorly understood.

Objective Therapeutic strategies silencing and reducing the hepatitis B virus (HBV) reservoir, the covalently closed circular DNA (cccDNA), have the potential to cure chronic HBV infection. We aimed ...

Researchers discovered a previously unknown function of RNA, potentially opening the door to new ways to treat cancer and neurodegenerative diseases.

DNA analysis is considered the gold standard for identifying victims of mass fatalities. But how does it work?

When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there ...

An international research team has deciphered a mechanism of the evolutionary arms race in human cells. The findings provide ...