An effective approach in the development of novel antivirals is to target the assembly of viral capsids by using capsid assembly modulators (CAMs). CAMs targeting hepatitis B virus (HBV) have two ...

The capsid of the hepatitis B virus has a very unique structure. It is composed of many monomers which interact to provide flexibility to its structure and function.

SHANGHAI, June 14, 2022 /PRNewswire/ -- Shanghai Zhimeng Biopharma announces that it will report the positive results obtained from a phase 1b study on its HBV capsid inhibitor ZM-H1505R in the ...

Shanghai Zhimeng Biopharma announces that it will report the positive results obtained from a phase 1b study on its HBV capsid inhibitor ZM-H1505R in the International Liver Congress in June 22-26, ...

Aligos Belgium presented research on ALG-005398, a first representative of a series of non-heteroaryldihydropyrimidines (HAPs) class I capsid-assembly modulators, that was identified using ...

A viral capsid is a structure that contains a virus's genetic material; in the case of hepatitis B, the capsid is an icosahedral structure about 36 nanometers in diameter and composed of 240 ...

A viral capsid is a structure that contains a virus’s genetic material; in the case of hepatitis B, the capsid is an icosahedral structure about 36 nanometers in diameter and composed of 240 identical ...

Our findings shed light on the dynamic aspects of the HBV capsid structure known to be central for its different functions. They lead us to advance a new hypothesis in signaling envelopment ...