HBV viral particles comprise a double-stranded DNA genome in the form of relaxed circular DNA (rcDNA), containing 3,020–3,320 nucleotides within a capsid made up of hepatitis ... discovered a unique ...

Aligos Therapeutics is a clinical-stage biotechnology company focused on improving patient outcomes through best-in-class ...

Chronic hepatitis B (CHB) is a long-term infection of the liver caused by the hepatitis B virus (HBV). While acute hepatitis B infection is often resolved by the immune system, CHB occurs when the ...

AI-assisted adeno-associated virus (AAV) capsid engineering has transformative potential in terms of accelerating and optimizing the development of gene therapies. That’s the view of Fangzhi Tan ...

This diagnostic tool could help eliminate hepatitis B by preventing mother-to-child transmission during childbirth, especially in low- and middle-income countries. Hepatitis B is a liver ...

A major challenge lies in the virus's structure and regulatory mechanisms, which have remained largely unclear. In particular, scientists have long struggled to fully understand its nucleocapsid ...

The American Gastroenterological Association (AGA) has released an updated clinical practice guideline on the prevention of hepatitis B virus reactivation (HBVr) in at-risk persons. The document ...

Get Instant Summarized Text (Gist) Chronic hepatitis B (CHB) patients with metabolic dysfunction-associated steatotic liver disease face increased mortality risks. Metabolic disorders like ...

The 3.0 Å resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the ...

A hepatitis B health alert has been issued to hundreds of mums and children who were admitted to the Nepean Hospital Birth Unit between 2013 and 2024. A health alert was issued after NSW Health ...