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A near-atomic level map of Zika virus shows its ... The information may also be useful for designing treatments such as antiviral drugs or antibodies that interfere with E glycoprotein function.
Glycoproteins also serve important functions in infectious disease, with glycoprotein receptors expressed on viral capsids involved in both recognition and infection of viable host cells. 20 The ...
The virus is primarily transmitted to people from ticks and livestock animals with a case fatality rate of up to 40%. There are currently no approved vaccines against the virus.
A second antibody, called odesivimab (REGN3471), binds to amino acids on the glycoprotein's receptor-binding site, preventing the virus from attaching itself to human cells.
Henipavirus glycoprotein architecture suggests therapeutic strategies Cryoelectron microscopy studies of Nipah and Hendra viruses may provide blueprints for vaccine ...
He studies bat immunity to many dangerous viruses, and conducts molecular structure and function studies of the infectivity machinery in coronaviruses, other related viruses, and henipaviruses.
Ross River Virus Glycoprotein-Pseudotyped Retroviruses and Stable Cell Lines for Their Production . C. Matthew Sharkey, Cynthia L. North, Richard J. Kuhn and David Avram Sanders. Pseudotyped ...
To date, Epstein-Barr virus (EBV) has escaped the attentions of vaccines and therapeutics. That EBV should be so shy frustrates scientists, who are well aware of EBV’s depredations.
This month’s story comes from the Bloom lab using their signature deep mutational scanning technique to identify mutations in the surface protein of Lassa virus -called glycoprotein- that escape ...
A near-atomic level map of Zika virus shows its structure to be largely similar to that of dengue virus and other flaviviruses, but with a notable difference in one key surface protein. The ...
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