Methotrexate, a common treatment for rheumatoid arthritis, can cause folate deficiency. Natural folate can be consumed from leafy vegetables. A doctor may prescribe folic acid supplementation to ...

The authors argue that folate supplementation should be administered only in circumstances leading to folate deficiency to prevent methotrexate adverse effects.

Folic acid deficiency anemia leads to fatigue, weakness, and irritability. ... Drugs such as methotrexate, phenytoin, sulfasalazine, and barbiturates can block folate absorption.- ...

Folic acid is the synthetic form of folate, ... Doctors may use folic acid to support a methotrexate prescription for rheumatoid arthritis. ... Folic acid deficiency. https: ...

Folate deficiency. Ascites, pleural effusions: evacuate fluid, monitor for toxicity and reduce dose or discontinue if needed. Elderly (use low doses and monitor closely).

Study: Folic acid and methotrexate use and their association with COVID-19 diagnosis and mortality: a case–control analysis from the UK Biobank.Image Credit: Pixel-Shot / Shutterstock ...

Folic acid supplements are prescribed for people with sickle cell disease, high-risk pregnancies, as well as for those who are taking anti-seizure medications and methotrexate (a drug used to ...

Folic acid deficiency can also occur in pregnancy, as people require higher levels of folic acid during pregnancy and breastfeeding. Alcohol use disorder (AUD) is also a significant cause of folic ...