New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses ...

Osteoarthritis disproportionally affects postmenopausal women, and a biological mechanism for why this occurs has been largely unkown, hindering development of effective treatments. That is in part ...

Regenerative medicine is a field of science that aims to heal or replace damaged cells, tissues, and organs for patients who suffer injuries or degenerative disorders. It encompasses tissue ...

These secrete large amounts of the cartilage extracellular matrix, which contains collagen and proteoglycans. Cartilage has limited repair capacity once damaged.

Cartilage’s biomechanical properties – it is strong but flexible – are due to cells called chondrocytes secreting large amounts of collagen-rich extracellular matrix (ECM), which surrounds ...

Semi-quantitative analysis utilizing a modified histological grading system, including parameters such as cellular morphology, matrix staining, surface regularity, thickness of cartilage, subchondral ...

Introduction: Osteoarthritis (OA) is a degenerative disease of the joints characterized by cartilage degradation and synovial inflammation. Due to the complex pathogenesis of OA, multifaceted ...

MedSkin Solutions Dr. Suwelack AG is pleased to announce the publication of a new study in the International Wound Journal titled 'Comparison of cell-scaffold interactions in a biological and a ...

One recent study in mice uncovered that menopause led to a drop in 17beta-estradiol and progesterone, which increased cartilage aging, degeneration, and disassembly of the extracellular matrix.

Costochondritis, also known as chest wall pain syndrome, is the inflammation of the cartilage of the rib cage. Chest pain near the sternum (breastbone) is the primary symptom. It is sometimes severe ...