In the mid-1800s, Lionel Smith Beale, an English physician and microscopist at King’s College in London, peered through his microscope at a smear of saliva and mucus coughed up by a man with cancer of ...

Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating ...

Storage of eukaryotic DNA in small, compact nuclei requires that this DNA be tightly coiled and compacted in the form of chromatin. However, the structure of chromatin also appears to serve a ...

Chromatin is a mixture of DNA and proteins that form the chromosomes found in the cells of humans. The study found that a ...

Every cell in your body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These ...

When genes are coiled and compacted into chromatin, they're no longer accessible to transcription factors. So how does the cell know where to uncoil in a process called chromatin remodeling?

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D ...

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

ChromoGen: A quick method to determine 3D genomic structures using generative AI, enabling the prediction of thousands of ...