Inflammation and Scarring of the Bile Ducts: Causes, Diagnosis, and Treatments
Bile duct inflammation and scarring, known as cholangiopathies, can disrupt bile flow, leading to liver damage and ...
The Lancet24d
Biliary Atresia – emerging diagnostic and therapy opportunities
2Dr. Li Dak-Sum Research Centre, the University of Hong Kong, Hong Kong 3Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 4Department of Surgery, ...
Nature27d
Biliary tract disease articles from across Nature Portfolio
Ceramide metabolism has garnered increasing attention in liver diseases, but its role in cholestatic liver injury remains unclear. Here the authors show that targeting ACER3, a ceramidase ...
gut.bmj1mon
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction
Endoscopic ultrasound (EUS) has been suggested as the primary modality in lieu of endoscopic retrograde cholangiopancreatography (ERCP) for drainage of malignant distal biliary obstruction. However, ...
Cure Today1mon
Understanding Biliary Tract Cancer and The Current Standard of Care
An expert explains what biliary tract cancers are and the current landscape of treatment as well as future advancements. In the treatment of newly diagnosed biliary tract cancer, the current standard ...
Frontiers7mon
Anatomical classification of advanced biliary tract cancer predicts programmed cell death protein 1 blockade efficacy
Background: Immune checkpoint blockade (ICB)-based immunotherapy has inspired new hope for advanced biliary tract cancer (BTC) treatment; however, there are no prior studies that primarily focus on ...
Frontiers3y
Efficacy and Safety of Anti-PD1/PDL1 in Advanced Biliary Tract Cancer: A Systematic Review and Meta-Analysis
Background: Anti-programmed cell death protein 1 and its ligand (anti-PD1/PDL1) have been proposed as a promising therapeutic option for advanced biliary tract cancer (aBTC). Given the scarce ...