Therefore, new treatment methods are urgently needed. In this study, we found that proteins derived from stressed mesenchymal stem cells (PDSSCs) can be utilized to treat AGA in a mouse model.

Human mesenchymal stromal/stem cell (hMSC) lines were modified to knock out vascular endothelial growth factor (VEGF) and Runt-related transcription factor 2 (RUNX2) and assessed for their capacity to ...

In stem cell populations, particularly adult stem cells, CD47 plays a crucial role in maintaining self-renewal and tissue regeneration capacities 53, 54. It regulates stem cell survival and ...

According to the Australian biotech, Ryoncil is the “first mesenchymal stromal cell (MSC) therapy” approved in the U.S. Graft-versus-host disease (GVHD) is a complication that typically develops in ...

Keywords: planar microelectrode, surface charge, macrophage, mesenchymal stem cells, polarization phenotype, osteogenesis Citation: Chen H, Xu C, Huang Q, Chen Y, Cheng K, Wang H and Chen X (2024) ...

Keywords: mesenchymal stem cells, uniaxial cyclic stretching, differentiation, chromatin accessibility, mechanotransduction, mechanobiology, tissue engineering Citation: Zhang D, Zhang R, Song X, Yan ...

Background and Purpose— Stroke is a leading cause of long-term disability. Limited treatment options exist for patients with chronic stroke and substantial functional deficits. The current study ...

Objective—Therapeutic angiogenesis with cell transplantation represents a novel strategy for severe ischemic diseases. However, some patients have poor response to such conventional injection-based ...

In many adult tissues, mesenchymal stem cells (MSCs) are closely associated with perivascular niches and coexpress many markers in common with pericytes. The ability of pericytes to act as MSCs, ...

Although high-throughput screens using genome-scale siRNA libraries have been successfully carried out in mammalian cells (11 – 13), effective application of arrayed synthetic siRNA library in stem ...