Background At least 60% of stroke, 40% of dementia and 35% of late-life depression (LLD) are attributable to modifiable risk ...

Background Previous natural history studies highlighted a consistent heterogeneity of disability trajectories among ...

Background Many common neurological disorders are associated with advancing chronological age, but their association with biological age (BA) remains poorly understood. Methods We studied 325 870 ...

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Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. The aim of this study was to examine the concept of apathy as it is ...

Correspondence to Dr Ruth Ann Marrie, Internal Medicine, University of Manitoba College of Medicine, Winnipeg, MB R3A 1R9, Canada; rmarrie{at}hsc.mb.ca Pain can be one of the worst symptoms of ...

Dr G Midroni, Neurophysiology laboratory, St. Michael’s Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8. Telephone 00416 864 5193; fax 00416 864 6095. A 22 year old woman with recently ...

Correspondence to Professor Didier Leys, Neurology, Stroke Unit, University of Lille, Lille 59000, Hauts-de-France, France; didier.leys{at}univ-lille.fr Objective To identify in patients who survived ...

Objective APOE is a strong risk factor for Alzheimer’s disease (AD) and associated with higher low-density lipoprotein cholesterol (LDL-C) levels. Moreover, LDL-C is associated with the development of ...

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New onset refractory status epilepticus (NORSE) can result in significant morbidity and mortality. Cryp- togenic NORSE where aetiology is unidentified, can occur in up-to half the cases. We present ...

Correspondence to: Professor Alan J Thompson Institute of Neurology, Queen Square, London WC1N 3BG, UK; a.thompsonion.ucl.ac.uk Spasticity is a common symptom seen in many neurological conditions, ...