Keywords protein synthesis, amino acids, mRNA, ribosome, tRNA, initiation factors, dynamic interactions, translation, genetic instructions Email us at [email protected] if you have questions ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Specifically, eIF-5A helps when the ribosome encounters challenging parts of mRNA, which would otherwise cause the ribosome to stall. eIF-5A contains a unique amino acid called hypusine.

The nucleotide sequence in mRNA is recognized in triplets, called codons. The ribosome moves along the single strand mRNA, and when a complimentary codon sequence belonging to amino acid bearing ...

This represents an important development in delivering mRNA to the cell types that would be key in treating neurodegenerative diseases; ... a 29-amino-acid segment of that protein.

Amino acids can catalyze RNA polymerization under mild, prebiotic conditions, increasing RNA formation by up to 100-fold through acid-base catalysis involving their amine groups.

Scientists are making a case for adjusting our understanding of how exactly genes first emerged. For a while, there’s been a consensus about the order in which the building-block amino acids ...

In a new paper in Nano Letters, the researchers demonstrate how peptides -- short strings of amino acids -- can serve as precise targeting molecules, enabling LNPs to deliver mRNA specifically to ...