Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working ...

Capital Medical University, in collaboration with the Chinese Academy of Sciences, reports that betaine, a molecule produced ...

SAN DIEGO, CA, USA I June 30, 2025 I Arcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a commercial messenger RNA medicines company focused on the development of ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

Keywords protein synthesis, amino acids, mRNA, ribosome, tRNA, initiation factors, dynamic interactions, translation, genetic instructions Email us at [email protected] if you have questions ...

Specifically, eIF-5A helps when the ribosome encounters challenging parts of mRNA, which would otherwise cause the ribosome to stall. eIF-5A contains a unique amino acid called hypusine.

Peptide-guided nanoparticles deliver mRNA to neurons Next step toward mRNA treatments for diseases like Alzheimer's Date: December 17, 2024 Source: University of Pennsylvania School of Engineering ...