While something as mild as indigestion, gas, bloating or anxiety about an upcoming test or public speech can all cause varying degrees of tummy troubles, there are sometimes more serious medical ...

Toxic megacolon can also ... Inflammatory bowel diseases include a group of chronic conditions such as Crohn's disease and ulcerative colitis that may include inflammation of the colon as one of ...

Considered the most serious complication of ulcerative colitis, toxic megacolon is the most extreme (and potentially life-threatening) form of fulminant colitis. It’s rare, ...

The purpose of this study is to assess the efficacy and safety of RO7790121 (formerly PF06480605 and RVT-3101) in patients with moderately to severely active ulcerative colitis (UC). RO7790121 is a ...

Bowel Perforation and Toxic Megacolon Bowel perforation is a rare but potentially life-threatening complication of ulcerative colitis. It is more common in those with long-standing, severe UC whose ...

Severe relapse of ulcerative colitis and toxic megacolon has been documented in the presence of coexisting infections such as C. difficile or CMV; therefore, these infections have to be excluded.

Fulminant colitis progresses rapidly, causing severe inflammation, systemic toxicity, and complications like toxic megacolon, bowel perforation, and sepsis. Prompt treatment can reduce these risks ...

Toxic megacolon is a rare, ... A proctocolectomy may be preferred in people with ulcerative colitis, as a j-pouch can then be created during a second surgery, after the recovery from toxic megacolon.

Ulcerative colitis can happen at any age, even in children, but is more commonly diagnosed in young adulthood, such as in the teens or 20s, ... “If a patient has severe disease, they could develop ...

Ulcerative colitis may lead to toxic megacolon when inflammation in the colon’s inner lining reaches the inner areas of the large intestine. This causes your large intestine to stop working and ...

Clinical presentation of Crohn’s, ulcerative colitis, and indeterminate colitis: Symptoms, extraintestinal manifestations, and disease phenotypes. Semin Pediatr Surg . 2017;26(6):349-355. + See More ...