Ulcerative colitis may lead to toxic megacolon when inflammation in the colon’s inner lining reaches the inner areas of the large intestine. This causes your large intestine to stop working and ...

As its name suggests, toxic megacolon is a serious complication that can occur in people who have inflammatory bowel disease (IBD). The condition is more common in people with ulcerative colitis ...

Considered the most serious complication of ulcerative colitis, toxic megacolon is the most extreme (and potentially life-threatening) form of fulminant colitis. It’s rare, ...

Considered the most serious complication of ulcerative colitis, toxic megacolon is the most extreme (and potentially life-threatening) form of fulminant colitis. It’s rare, ...

A person may develop toxic megacolon if their colon has inflammation due to conditions such as Crohn’s disease or ulcerative colitis, or infections such as Clostridioides difficile (C. difficile).

Severe relapse of ulcerative colitis and toxic megacolon has been documented in the presence of coexisting infections such as C. difficile or CMV; therefore, these infections have to be excluded.

Fulminant colitis progresses rapidly, causing severe inflammation, systemic toxicity, and complications like toxic megacolon, bowel perforation, and sepsis. Prompt treatment can reduce these risks ...

Here's what colitis is, ... Toxic megacolon can ... Inflammatory bowel diseases include a group of chronic conditions such as Crohn's disease and ulcerative colitis that may include ...

Toxic megacolon can also ... Inflammatory bowel diseases include a group of chronic conditions such as Crohn's disease and ulcerative colitis that may include inflammation of the colon as one of ...

In general, ulcerative colitis has an incidence of 9–20 cases per 100,000 persons per year, according to StatPearls Publishing. The research further notes that its prevalence is 156-291 cases ...

TOXIC megacolon developing during the course of fulminating ulcerative colitis was first described in 1950 by Marshak and Lester. 1 Five years later Lumb et al. 2 reported 7 cases of "ulcerative ...