This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in ...

Membrane proteins are proteins found in cell ... the process of oligomer formation of the transmembrane pore structure has not yet been elucidated. Here, the authors examine and compare the ...

Structure-based drug design is the design and ... a modular TFRC-based covalent peptide degradation platform that effectively degrades membrane protein PD-L1. This approach significantly ...

Nov. 13, 2024 — The use of biologic and targeted therapies for children with juvenile idiopathic arthritis (JIA) surpassed more typical therapies in recent years, according to ...

We thank Uwe Appelt and Markus Mroz of the Core Unit Cell Sorting and Immunomonitoring facility for their technical support in synovial cell sorting.