Washington State University researchers have discovered how the bacteria that cause anaplasmosis and Lyme disease hijack ...

Among the defining achievements of SG60 is Singapore’s transformation into a global health innovator. The latest chapter ...

Scientists have unearthed a rare class of ultra-potent antibodies derived from llamas that can neutralize a vast array of coronaviruses—including SARS-CoV-1 and multiple forms of SARS-CoV-2, both old ...

The team used a similar approach to model the dynamic transformations that the SARS-CoV-2 Spike protein undergoes after binding its receptor and while literally moving towards fusion. To accomplish ...

Multidisciplinary AI- and physics-driven modeling of the viral fusion process has enabled the discovery of an orally available drug inhibiting infection with multiple coronaviruses.

Though it is near the receptor-binding domain and is known to be targeted by some antibodies, function of the N-terminal domain in SARS-CoV-1 and -2 spike proteins is not completely understood.

Dec. 8, 2020 — The binding of a SARS-CoV-2 virus surface protein spike -- a projection from the spherical virus particle -- to the human cell surface protein ACE2 is the first step to infection ...

Mutations in SARS-CoV-2 spike protein receptor-binding domains may result in escape variants resistant to therapeutics and vaccines. ScienceDaily . Retrieved May 3, 2025 from www.sciencedaily.com ...

Each monomer of the spike protein shows the receptor binding domain (RBD) in green, orange and magenta, which contains a receptor binding motif in cyan on the top. Mutations emerged in the SARS ...

It could make the virus’s spike protein unstable so that it can’t latch quickly onto a cell, for example. But inside someone with a weak immune system, viruses may be able to gain a new ...