SARS-CoV-2 infection associated with increased risk of cardiac events
A new study found severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was associated with the rapid growth ...
Medical Xpress29d
Genetic mutation linked to higher SARS-CoV-2 risk
SARS-CoV-2 is the virus that spreads COVID-19 ... reversed the increased ACE2 expression on lung, intestinal, and immune cells, thus reducing susceptibility to viral invasion." ...
News Medical26d
Tofacitinib reduces SARS-CoV-2 infection risk in patients with PTPN2 deficiency
The SARS-CoV-2 spike (S) protein mediates its attachment ... The expression of ACE2, which is present at high concentrations on both lung and intestinal epithelial cells, is directly related ...
Frontiers8d
SARS-CoV-2 bivalent mRNA vaccine with broad protection against variants of concern
RBMRNA-405 efficiently blocked infectious viral replication and lung injury in both Omicron- and Delta-challenged K18-ACE2 mice. Conclusion: Our data suggest that RBMRNA-405 is a promising bivalent ...
thorax.bmj10d
S145 SARS-CoV-2 infection and pro-fibrotic signaling in the lung – defining the role of αvβ6
Background and Aims The SARS-CoV-2 (COVID-19) pandemic caused significant global mortality and morbidity. Recent studies report residual lung abnormalities (RLA) and evidence of lung fibrosis in some ...
Frontiers9d
Neutrophilic inflammation promotes SARS-CoV-2 infectivity and augments the inflammatory responses in airway epithelial cells
Furthermore, examination of COVID-19 explanted lung tissue revealed a series of epithelial pathologies associated with the infiltration and activation of neutrophils, indicating neutrophil activity in ...