eLife18d
Secondary structure of the SARS-CoV-2 genome is predictive of nucleotide substitution frequency
SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.
Scientific American1d
Four Ways the COVID-Causing Virus Changed Science
Kei Sato was looking for his next big challenge five years ago when it smacked him — and the world — in the face. The ...
Frontiers15d
Bioinformatic analysis of defective viral genomes in SARS-CoV-2 and its impact on population infection characteristics
DVGs (Defective Viral Genomes) are prevalent in RNA virus infections. In this investigation, we conducted an analysis of high-throughput sequencing data and observed widespread presence of DVGs in ...
Frontiers15d
Immune-profiling of SARS-CoV-2 viremic patients reveals dysregulated innate immune responses
The raw reads were aligned to the Hg38 human genome database and SARS-CoV-2 Wuhan-Hu-1 strain was used as reference for virus alignment. Human Interferon stimulated genes were downloaded from the ...
C&EN20d
Targeting Two-Tetrad RNA G-Quadruplex in the SARS-CoV-2 RNA Genome Using Tetraphenylethene Derivatives for Antiviral Therapy
Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Third Milestone, Faridabad − Gurugram Expressway, Faridabad, Haryana 121001, India ...
How the pandemic changed the world of disease control for worse — and for better
Five years after the World Health Organization declared a global pandemic, there has been progress — and backsliding in the ...
The Scientist2m
Viruses That Mimic Human Proteins May Be More Common than Previously Thought
A screen of human-infecting viruses identified extensive examples of viral proteins that resembled human sequences, which ...
KTVU FOX 26d
COVID 5 years later: health office retires, families reflect
Half a decade since coronavirus SARS-CoV-2 plunged the world into a pandemic, the scars are still healing for those who lost ...