It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about ...

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Identification of HKU5-CoV-2 (a member of the HKU5 lineage 2), a new merbecovirus found in bats of Zhejiang, Anhui, and ...

More information: Shun Nakamura et al, Structure-guided engineering of a mutation-tolerant inhibitor peptide against variable ...

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

The SARS-CoV-2 virus has been observed to infect human neurons ... where the virus is first taken up into an intracellular structure known as an endosome. In the endosome, enzymes such as cathepsins ...

Viruses like SARS-CoV-2 use sugar molecules to hide from the immune system, but scientists at Scripps Research have designed ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

SARS-CoV-2, the virus responsible for COVID-19 ... However, mutations in the spike protein can alter its structure, reducing the effectiveness of these inhibitors. In a significant breakthrough ...