In a comprehensive Genomic Press Innovators & Ideas interview, Dr. Danielle Beckman reveals how her passion for microscopy ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

The majority of children do not need a tonsillectomy.” But when done for the right reasons, tonsillectomy offers a meaningful ...

Background The COVID-19 pandemic continues to be a worldwide threat and effective antiviral drugs and vaccines are being developed in a joint global effort. However, some elderly and ...

Could a Neanderthal gene offer protection against the severity of Covid-19? This video discusses the Gene OAS1 and its ...

The World Health Organization's probe into the cause of COVID-19 has not resulted in a definitive reason, with its ...

Scientists remain divided on the origins of the COVID-19 virus, with limited data and no consensus reached after years of ...

For example, both SARS-CoV-2 and SARS-CoV-1 deletion and substitution mutations of Nsp1 in the C-terminal motif IDR significantly destabilize the structure of Nsp1 (Rezaei et al., 2022). In fact, ...

SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells. Emerg Microbes Infect. 2022; 11:277-283. Crossref. Scopus ...

3 Protective mechanisms of NAbs against SARS-CoV-2 infection. NAbs employ a range of proposed defensive mechanisms to eradicate SARS-CoV-2, including direct inhibition of viral entry to host cells ...

We then assessed the properties of NB.1.8.1 by virological experiments. A lentivirus-based pseudovirus assay showed that the infectivity of NB.1.8.1 was significantly higher (2·5-fold; p<0·0001) than ...

The key viral protein for infection by SARS-CoV-2 is the spike glycoprotein (S protein), mediating entry into host cells, which therefore represents a strong focus for the development of targeted ...