As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every ...

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

The spike protein of the coronavirus, or SARS-CoV-2, binds to ACE2, a receptor on the host cells ... “We simulated the electronic structure of the two interacting molecules and assessed how amino ...

CoV-2, a new merbecovirus found in bats across China, that utilises the ACE2 receptor for cellular entry—raising concerns ...

Viruses like SARS-CoV-2 use sugar molecules to hide from the immune system, but scientists at Scripps Research have designed ...

Specifically, we developed a statistical mechanics model that connects the thermodynamic properties of the virus's spike protein to its ability to spread. The key player in SARS-CoV-2's infection ...

SARS-CoV-2, the virus responsible for COVID-19 ... However, mutations in the spike protein can alter its structure, reducing the effectiveness of these inhibitors. In a significant breakthrough, a ...