Multidisciplinary AI- and physics-driven modeling of the viral fusion process has enabled the discovery of an orally available drug inhibiting infection with multiple coronaviruses.

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

WYS-633 also prevented SARS-CoV-1, MERS, and multiple SARS-CoV-2 variants from infecting cells ... discovery of drugs against a number of other virus families utilizing membrane fusion proteins, ...

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying ...

The WHO Scientific Advisory Group for the Origins of Novel Pathogens (SAGO), a panel of 27 independent, international, ...

The human body is naturally equipped with defenses to fight off viral infections. For a virus to successfully infect it, it must first overcome these defenses. To do so, viruses have evolved ...

The COVID-19 pandemic caused by SARS-CoV-2 presents a global health emergency. Therapeutic options against SARS-CoV-2 are still very limited but urgently required. Molecular tweezers are ...