The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

SARS-CoV-2 escapes from immune responses by cytotoxic T cells via impaired MHC-I expression which is caused by reducing both the amount and function of NLRC5 (Koichi Kobayashi).

SARS-CoV-2, the virus responsible for COVID-19 ... and omicron BA.5) , blocking viral entry into pre-treated cells and ...

Identification of HKU5-CoV-2 (a member of the HKU5 lineage 2), a new merbecovirus found in bats of Zhejiang, Anhui, and ...

A SARS-CoV-2 antibody, NT-108, exhibits potent therapeutic effects in vivo. Cryo-EM structure of the spike complexed with single-chain Fv of NT108 reveals its neutralizing mechanism, providing ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about its future evolution remain. New variants of the virus will likely emerge, ...

Athena Akrami has not been well since March 2020, when she first experienced symptoms of a SARS-CoV-2 infection. Although the initial infection cleared within weeks, more than a year later Akrami ...

In the cytoplasm, the virus harnesses the host cell’s internal mechanism to produce new viruses. While the ability of SARS-CoV-2 to infect human neurons ... acute respiratory syndrome coronavirus 2 ...

HKU5-CoV-2 is found in bats which which was discovered in China and uses the ACE2 receptor for cell entry. It is very similar to SARS-CoV-2 but as per the Wuhan Institute of Virology, HKU5-CoV-2 ...