Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm. Cytokines are small proteins released by many different cells in ...

When a healthy individual suffers from an acute infection, there is an expectation that their immune system will ramp up to fight the invading pathogens and then return to its baseline state. The ...

The importance of testing for SARS-CoV-2 has been emphasized since the beginning of the outbreak. Institutions all around the world have been rapidly developing PCR tests with the aim of fast, ...

When the COVID-19 pandemic first began, we saw how quickly the SARS-CoV-2 virus evolved. New variants emerged with mutations that increased transmissibility or helped the virus evade our immune ...

SARS-CoV-2-specific T cells in BALF exhibited profound activation, along with proliferative and multi-cytokine-producing capabilities and a glycolysis-driven metabolic signature, which were ...

Cellular and tissue damage, plus the resultant toxin spillage, the loss of selenium, and the cytokine storm initiated by increased levels of IL-6, all contribute to multiorgan failure.

It started as a respiratory illness – or so everyone thought. But it quickly became apparent that SARS-CoV-2, the virus that causes COVID-19, was so much more. "Since the beginning, the virus ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

Athena Akrami has not been well since March 2020, when she first experienced symptoms of a SARS-CoV-2 infection. Although the initial infection cleared within weeks, more than a year later Akrami ...