Scientists identified the mechanism by which a sea cucumber molecule inhibits sulfatase-2, an enzyme that’s often upregulated ...

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections.

A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake. Scientists had zeroed in ...

Two molecules found in various plants, including one extracted from birch, could prevent viruses as formidable as HIV, Ebola, ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Viral proteases, the key enzymes that regulate viral replication and assembly, are promising targets for antiviral drug discovery. Herpesvirus proteases are enzymes with no crystallographically ...

Small molecule inhibition of the PLpro protease domain significantly reduces viral loads in SARS-CoV-2 infection models, suggesting that PLpro is an excellent drug target for next generation ...

The creation of a new magnetic molecule could pave the way to build new, stamp-sized hard drives capable of holding the equivalent of 40,000 CDs' worth of music—that's three years of nonstop tunes!