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Rhinoviruses, perhaps best known as one cause of the common cold, have complex surfaces made up of a mosaic of protein molecules. Groups of these proteins organize themselves into pentagonal and ...
The model reveals that the capsid, or protein shell, of rhinovirus C differs from those of rhinoviruses A and B, for which 3-D models are already known. A capsid, or protein shell, encases a virus ...
Like HIV, a rhinovirus consists of an RNA genome cocooned in a shell of proteins called a capsid. The virus attaches to the membrane of a host cell, injects its genetic material and then hijacks ...
Modeling of the human rhinovirus C capsid suggests a novel topography with insights on receptor preference and immunogenicity. Virology, 2014; 448: 176 DOI: 10.1016/j.virol.2013.10.006; ...
The common cold virus (rhinovirus) is a tiny, almost round particle, containing the tightly packed genetic material surrounded by a protein shell (the virus capsid).
MADISON, Wis. – In a pair of landmark studies that exploit the genetic sequencing of the "missing link" cold virus, rhinovirus C, scientists at the University of Wisconsin-Madison have ...
Assembly of the rhinovirus capsid relies on the activity of a human enzyme, N-myristoyltransferase (NMT), which carries out modification of one of the viral capsid proteins, VP0, by a process ...
When rhinovirus infects the body, it hijacks the host genome to produce proteins it needs. For instance, to construct the shell, or capsid, it needs to reproduce, it relies on the human enzyme to ...
The electrostatics of the virus capsid surface are shown as a magenta-cyan spectrum. view more . Credit: James Geraets. ... Picornaviruses include rhinoviruses and enteroviruses.