More than 4,000 years ago, Egypt and Mesopotamia stood as two of the most complex societies on the planet. But the new DNA ...

Scientists have for the first time sequenced the most complete and oldest ancient Egyptian genome ever found—unlocking new ...

Artificial human DNA, or synthetic DNA (synDNA), would be made without biological parents by instead using chemicals. SynHG ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

“PDI is like a double agent,” Dr Shadfar explains. “In healthy cells, it repairs DNA and helps prevent disease. But in cancer, it gets hijacked — it ends up protecting the tumour instead of the body.

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break invol ...

At some point, RNA must have replicated itself before the evolutionary arrival of DNA and proteins, and now we might know how.

These physical spacers are known as L2 loops, and each insertion exposes the bases of three DNA nucleotides that are then available for the invading strand to pair to, probing for homology.

Measurement of the conformation of DNA in protein–DNA complexes is important to decipher the role of the DNA conformation and dynamics in protein recognition and function. In this work, we report a ...

Reference: “Human polymerase θ helicase positions DNA microhomologies for double-strand break repair” by Christopher J. Zerio, Yonghong Bai, Brian A. Sosa-Alvarado, Timothy Guzi and Gabriel C. Lander, ...