C&EN1mon
Relay Catalysis-Enabled Enantioselective Annulations of β,γ-Alkynyl-α-imino Esters with 1,3-Diones for the Divergent Synthesis of Chiral Oxacycles
The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.orglett.5c00233.
Frontiers2y
Effect of iodoacetic acid on the reproductive system of male mice
Spermatogenous cells are the site of spermatogenesis, Leydig cells are the site of testosterone synthesis, and Sertoli cells build ... and washed three times in phosphate-buffered saline (PBS). The ...
Frontiers2y
Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1
Carboxylic acids have been shown to be good phosphate bioisosteres (Burke and Lee, 2003; Elliott et al., 2012). Yet phosphonic acids could potentially better-replicate cognate TOP1-DNA substrate ...
eLife7y
Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function
Sphingosine can increase the concentration of calcium ions inside the cells, and when converted to a molecule called sphingosine 1 phosphate it forms a signaling molecule that regulates fundamental ...