The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.

New research reveals Parkinson’s disease may originate in the kidneys, where toxic protein buildup travels to the brain—offering fresh hope for early detection and treatment.

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a ...

Dark cerebral matter fades in Parkinson’s disease. Investigation of the human brain discloses a distinct dark discoloration of the substantia nigra and locus coeruleus within parts of the brainstem.

Parkinson's disease is a chronic progressive neurological disease that affects a small area of nerve cells (neurons) in an area of the brain known as the substantia nigra. These cells normally ...

The main neuropathological feature of Parkinson's disease is the loss of dopaminergic neurons in the substantia nigra pars compacta. Specifically, dopaminergic neurons in the ventral tier of the ...

Parkinson’s disease is a devastating condition whereby neurons in a specific region of the brain that controls movement lose functionality or die. This brain region is known as the substantia nigra — ...

Most Parkinson's symptoms stem from the loss or dysfunction of dopamine-producing neurons in a brain region involved in fine ...

Learn what you need to know about the substantia nigra. Discover its function, location, ... Conditions that affect the substantia nigra include: Parkinson's disease.

A Duke-led research team has identified a blood-based biomarker to diagnose Parkinson’s disease, ... the substantia nigra receives its names from the darkly pigmented cells that make up the tissue.