eLife9h
Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.
Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
The tumors in these mice showed high expression of cancer stem cell markers CD56 and CD20 ... long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer ...
Nature7y
Mixed cell therapy of bone marrow-derived mesenchymal stem cells and articular cartilage chondrocytes ameliorates osteoarthritis development
Cell proliferation was assessed using (3-(4,5 ... using a panel of antibodies covering the expression of chondrogenic marker (ACAN and COL2), angiogenesis marker (VEGF), angiogenesis inhibitor ...
Taiwan News10d
A chronographic analysis of MSC's rollercoasting journey
December 2024, immediately following the approval of the world's first mesenchymal stromal cells clinical trial, the U.S. FDA ...