The global mast cell tumor treatment market is on a strong growth trajectory, with market projections estimating a valuation of USD 7,836.4 million by 2034. This reflects a steady CAGR of 3.4% from ...

Histamine makes lots of changes in your body. It adjusts your blood vessels and tissues so more immune cells can rush to the area. It makes a bunch of mucus. It tells the muscles in your airways, ...

The following is a summary of “Novel Bradykinin Detection In The Diagnostic Workup Of Patients With Recurrent Angioedema ...

Systemic mastocytosis is a disease where too many abnormal mast cells (a type of white blood cell) build up in your skin and other organs. You might get a variety of symptoms, including itchy skin ...

Allergic inflammation plays a big role in allergy reactions and contributes to the itching and chewing commonly seen with ...

1 Pathogenesis of CSU: The Role of Mast Cells Understanding the role of mast cells is key to grasping the underlying mechanisms of CSU. Mast cells, particularly the MCTC subtype found in the skin ...

BLU-808 achieved dose-dependent serum tryptase reductions exceeding 80 percent, reflecting evidence of mast cell target engagement. BLU-808 had a half-life supporting once-daily oral dosing and ...

CDX-622 inhibits SCF and TSLP-dependent inflammatory signatures in human skin -- Phase 1 study in healthy volunteers ongoing -HAMPTON, N.J., ...

At the recent AAAAI/WAO meeting, Blueprint Medicines Corp. presented the in vitro and in vivo characterization of BLU-808, a selective inhibitor of wild-type KIT, a transmembrane receptor tyrosine ...

Jasper expects to report data around mid-year 2025 from 4 cohorts: the 240mg single dose cohort (4 additional patients), 240mg Q8W cohort (8 patients), 240mg followed by 180mg Q8W cohort (8 patients), ...