G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

Inositol supplements show significant benefits for hormonal disorders, insulin sensitivity, and fertility issues, offering a natural approach.

A Review of the Research Progress and Application of Skin Care Ointments in Chronic Eczema Treatment ...

Extracellular signalling molecules are cues, such as growth factors, hormones ... are recognized by cognate receptors on the surface of target cells to initiate intracellular signalling cascades ...

In this important study, Li and others identified cell membrane receptors for juvenile hormone (JH), a terpenoid hormone in insects that regulates their development and reproduction. While ...

Figure 6. A diagram illustrating CAD96CA and FGFR1 transmitting juvenile hormone signal for gene expression. (1) JH binds to cell membrane receptors CAD96CA and FGFR1 to increase intracellular calcium ...

and growth hormone receptor (GHR), the intracellular fate of the IFNAR receptor complex upon its endocytosis has long remained mysterious. In contrast to IFNAR1, whose final fate is degradation in the ...

Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone estrogen and explain why they are less susceptible to certain infectious ...

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

More information: Xiaoyong Chen et al, A lupus-derived autoantibody that binds to intracellular RNA activates cGAS-mediated tumor immunity and can deliver RNA into cells, Science Signaling (2025).

Thyroid Peroxidase (TPO) is a 110 kD membrane bound hemo-glycoprotein with a large extracellular domain, and a short transmembrane and intracellular domain. TPO is involved in thyroid hormone ...