Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular ...

Hepatitis δ virus (HDV) is subviral in that it depends upon hepatitis B virus (HBV) for envelope proteins. HDV has an RNA genome smaller ... which is linear, less than full length, 5′-capped ...

Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.

Precision BioSciences (DTIL) announced that the U.S. Food and Drug Administration or FDA has cleared the Investigational New Drug application ...

However, I was fascinated to discover that viruses like hepatitis B hijack epigenetic mechanisms, even using human DNA-packaging proteins to regulate their activity.” Not long after, study first ...

Therefore, a better treatment is needed. A crucial HBV protein called X is necessary for the virus to establish an infection in a host cell, and viral gene expression. But since X gene is in the viral ...

Seroconversion from HBeAg to anti-HBe is usually associated with serum HBV DNA undetectable by hybridization technology and remission of liver disease. Nevertheless, a certain proportion of anti ...

one of the smallest DNA viruses in existence, enters susceptible liver cells — known as hepatocytes — and begins replicating. Inside the hepatocytes, HBV produces a surplus of viral antigens ...

ELIMINATE-B Phase 1 dose finding study for chronic Hepatitis B executing on schedule with completion of first dose administration for cohort 1 (n=3 patients) PBGENE-HBV, the first LNP gene editing ...