Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.

The presence and the positioning of nucleosomes on DNA can be important in directing cellular mechanisms to transcribe some genes. We found that to be the case for the HBV gene encoding protein X — ...

Atomic force microscopy images show hepatitis B DNA in its natural state ... The Risca Lab studies the 3D architecture of the genome and how the packaging of DNA helps to control the transcription ...

Worldwide, hepatitis B is thought to be the second deadliest infection; about 5% of the global population are infection and it can lead to liver cancer. | Microbiology ...

Hepatitis B is a liver infection that affects ... The Risca Lab studies the 3D architecture of the genome and how the packaging of DNA helps to control the transcription of genes.

Early in infection, HBV establishes an independent “minichromosome” consisting of the viral covalently closed circular DNA (cccDNA) genome and host histones. But as the authors noted ...

Hepatitis B is a liver infection that affects ... The Risca Lab studies the 3D architecture of the genome and how the packaging of DNA helps to control the transcription of genes.

PBGENE-HBV, which comprises an ARCUS-encoding ... to cause expression/add function), elimination (removing a genome e.g. viral DNA or mutant mitochondrial DNA), and excision (removing a large ...

Occult HBV infection is defined by the existence of HBV DNA in serum, lymphoid cells (PBMC) and/or the liver and virus-genome replicative intermediates (i.e., covalently closed circular DNA ...