Osteoarthritis disproportionally affects postmenopausal women, and a biological mechanism for why this occurs has been largely unkown, hindering development of effective treatments. That is in part ...

One recent study in mice uncovered that menopause led to a drop in 17beta-estradiol and progesterone, which increased cartilage aging, degeneration, and disassembly of the extracellular matrix.

Cartilage’s biomechanical properties – it is strong but flexible – are due to cells called chondrocytes secreting large amounts of collagen-rich extracellular matrix (ECM), which surrounds ...

Cartilage comprises two major components, the extracellular matrix (the surrounding proteins that provide structure) and chondrocytes, the resident cell population. In OA, the health of both these ...

Bioink manufacturers play an important role in bioprinting. Explore our list to see which companies are on the market.

A dual-responsive hydrogel offers a breakthrough in osteoarthritis treatment by inhibiting neurovascularization and reducing ...

Objective Glenohumeral (GH) osteoarthritis (OA) is the third most common large joint disease, after hip and knee OA. This ...

Cartilage Protection and Regeneration Effect of MSCs-EV ... dynamic-light scattering; ECM, extracellular matrix; ECM/GelMA/exosome, extracellular matrix/gelatin methacrylate/exosome; ERK 1/2, ...

Biodegradable materials, including polymers, degrade naturally, reducing pollution and offering eco-friendly solutions for ...