The viral vector space needs a lot of DNA to make AAV vectors, for example. You need 3–4 pieces of DNA to transfect into cells to produce these factors at scale.

The company’s proprietary synthetic DNA vector, which is known as “doggybone DNA” or dbDNA™ provides a highly effective solution to the plasmid bottleneck and current industry limitations.

AAV Vectors. AAVs are single-stranded DNA viruses that require co-infection with other viruses, mainly adenoviruses, to replicate. When used as gene therapy vehicles, researchers generate recombinant ...

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to a new gene therapy for Amyotrophic Lateral ...

"Based on insights from six in-depth reports, this review explores how breakthroughs in sequencing, RNAi, and viral vector technologies will shape the future of biotech through 2029.”Boston, July 07, ...

The Gene Vector Core was awarded the Blue Flame Award. The award is given to scientists who have at least one plasmid deposited that has been distributed at least 100 times. The Gene Vector Core was ...

Gene therapies treat or prevent disease by tweaking the content or expression of cells' DNA. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works ...

Charles River Laboratories International, Inc. (NYSE: CRL) and Captain T Cell, a spinoff from the renowned Max Delbrück Center Berlin, Germany, today ...

Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years ...