A crash has closed all eastbound lanes of Interstate 40 East, according to the Tennessee Department of Transportation.

A multi-vehicle crash on I-40 near Holbrook, Arizona, claimed five lives, including a high school student and a Colorado ...

An overturned semi-truck and two other vehicles collided on I-40, injuring two people and causing traffic disruptions.

A semi truck was involved in a crash on Interstate 40 on Wednesday morning, causing road blocks. The crash took place on I-40 ...

Authorities are working to identify additional human remains in the wreckage involving multiple vehicles along Interstate 40 ...

Two people were injured after a crash involving a flipped semi-truck led to major traffic delays on Interstate 40 in ...

RALEIGH, N.C. (WTVD) -- Two people were killed Sunday morning in a head-on crash on I-40 in Wake County, authorities said. It ...

A collision between a Memphis Police cruiser and an 18-wheeler caused some delays on Interstate 40 on Tuesday morning, the ...

The No. 2 seed St. John's Red Storm experienced a resurgence this season under legendary head coach Rick Pitino in just his ...

Five people who were killed in a multi-vehicle crash along Interstate 40 in northern Arizona last week have been identified.

A man and a woman were killed Sunday morning in a head-on crash on Interstate 40 in Raleigh. The crash was reported before 4 ...

HAVE MUCH MORE FROM HER LATER IN THE NEWSCAST. ALSO HAPPENING NOW A PART OF A BUSY HIGHWAY IN THE TRIAD IS CLOSED BECAUSE OF A CRASH. THIS IS A LIVE LOOK TONIGHT AT INTERSTATE 74 AT I-40 IN ...